Septerna, Inc. (SEPN)

Last Closing Price: 26.16 (2025-12-04)

Profile
Ticker
SEPN
Security Name
Septerna, Inc.
Exchange
NASDAQ
Sector
Healthcare
Industry
Biotechnology
Free Float
42,849,000
Market Capitalization
1,188,760,000
Average Volume (Last 20 Days)
369,623
Beta (Past 60 Months)
3.80
Percentage Held By Insiders (Latest Annual Proxy Report)
4.30
Percentage Held By Institutions (Latest 13F Reports)
Recent Price/Volume
Closing Price
26.16
Opening Price
26.40
High Price
26.80
Low Price
25.74
Volume
178,000
Previous Closing Price
26.55
Previous Opening Price
26.12
Previous High Price
26.65
Previous Low Price
25.46
Previous Volume
290,000
High/Low Price
52-Week High Price
29.73
26-Week High Price
29.73
13-Week High Price
29.73
4-Week High Price
29.73
2-Week High Price
29.73
1-Week High Price
29.68
52-Week Low Price
4.17
26-Week Low Price
9.85
13-Week Low Price
13.67
4-Week Low Price
17.55
2-Week Low Price
23.55
1-Week Low Price
25.46
High/Low Volume
52-Week High Volume
37,815,761
26-Week High Volume
1,522,000
13-Week High Volume
1,522,000
4-Week High Volume
1,522,000
2-Week High Volume
681,000
1-Week High Volume
295,000
52-Week Low Volume
96,056
26-Week Low Volume
104,000
13-Week Low Volume
117,000
4-Week Low Volume
151,000
2-Week Low Volume
178,000
1-Week Low Volume
178,000
Money Flow
Total Money Flow, Past 52 Weeks
1,696,192,203
Total Money Flow, Past 26 Weeks
665,471,666
Total Money Flow, Past 13 Weeks
434,710,149
Total Money Flow, Past 4 Weeks
178,438,432
Total Money Flow, Past 2 Weeks
89,946,140
Total Money Flow, Past Week
36,389,142
Total Money Flow, 1 Day
4,669,533
Total Volume
Total Volume, Past 52 Weeks
139,555,393
Total Volume, Past 26 Weeks
40,622,000
Total Volume, Past 13 Weeks
20,367,000
Total Volume, Past 4 Weeks
7,390,000
Total Volume, Past 2 Weeks
3,265,000
Total Volume, Past Week
1,331,000
Percent Change in Price
Percent Change in Price, Past 52 Weeks
3.85
Percent Change in Price, Past 26 Weeks
148.67
Percent Change in Price, Past 13 Weeks
85.27
Percent Change in Price, Past 4 Weeks
39.15
Percent Change in Price, Past 2 Weeks
10.05
Percent Change in Price, Past Week
-9.86
Percent Change in Price, 1 Day
-1.47
New High/Low in Price
Reached New 52-Week High Price
False
Reached New 26-Week High Price
False
Reached New 13-Week High Price
False
Reached New 4-Week High Price
False
Reached New 2-Week High Price
False
Reached New 1-Week High Price
False
Reached New 52-Week Low Price
False
Reached New 26-Week Low Price
False
Reached New 13-Week Low Price
False
Reached New 4-Week Low Price
False
Reached New 2-Week Low Price
False
Reached New 1-Week Low Price
False
Consecutive Days/Weeks of Increasing/Decreasing Price
Consecutive Days of Increasing Price
0
Consecutive Weeks of Increasing Price
3
Consecutive Days of Decreasing Price
1
Consecutive Weeks of Decreasing Price
0
Consecutive Days/Weeks of Increasing/Decreasing Volume
Consecutive Days of Increasing Volume
0
Consecutive Weeks of Increasing Volume
3
Consecutive Days of Decreasing Volume
1
Consecutive Weeks of Decreasing Volume
0
New High/Low in Volume
Had New 52-Week High Volume
False
Had New 26-Week High Volume
False
Had New 13-Week High Volume
False
Had New 4-Week High Volume
False
Had New 2-Week High Volume
False
Had New 1-Week High Volume
False
Had New 52-Week Low Volume
False
Had New 26-Week Low Volume
False
Had New 13-Week Low Volume
False
Had New 4-Week Low Volume
False
Had New 2-Week Low Volume
True
Had New 1-Week Low Volume
True
Moving Averages
Simple Moving Average (5-Day)
27.10
Simple Moving Average (10-Day)
27.09
Simple Moving Average (20-Day)
23.69
Simple Moving Average (50-Day)
22.15
Simple Moving Average (100-Day)
17.62
Simple Moving Average (200-Day)
12.79
Previous Simple Moving Average (5-Day)
27.79
Previous Simple Moving Average (10-Day)
26.78
Previous Simple Moving Average (20-Day)
23.33
Previous Simple Moving Average (50-Day)
21.96
Previous Simple Moving Average (100-Day)
17.47
Previous Simple Moving Average (200-Day)
12.69
Technical Indicators
MACD (12, 26, 9)
1.84
MACD (12, 26, 9) Signal
1.68
Previous MACD (12, 26, 9)
1.97
Previous MACD (12, 26, 9) Signal
1.64
RSI (14-Day)
58.82
Previous RSI (14-Day)
60.60
Stochastic (14, 3, 3) %K
67.86
Stochastic (14, 3, 3) %D
74.21
Previous Stochastic (14, 3, 3) %K
73.61
Previous Stochastic (14, 3, 3) %D
82.06
Upper Bollinger Band (20, 2)
31.36
Lower Bollinger Band (20, 2)
16.02
Previous Upper Bollinger Band (20, 2)
31.16
Previous Lower Bollinger Band (20, 2)
15.51
Income Statement Financials
Quarterly Revenue (MRQ)
21,495,000
Quarterly Net Income (MRQ)
8,173,000
Previous Quarterly Revenue (QoQ)
119,000
Previous Quarterly Revenue (YoY)
176,000
Previous Quarterly Net Income (QoQ)
-24,838,000
Previous Quarterly Net Income (YoY)
-20,523,000
Revenue (MRY)
1,075,000
Net Income (MRY)
-71,798,000
Previous Annual Revenue
151,000
Previous Net Income
567,000
Cost of Goods Sold (MRY)
Gross Profit (MRY)
1,075,000
Operating Expenses (MRY)
81,898,000
Operating Income (MRY)
-80,823,000
Non-Operating Income/Expense (MRY)
8,527,000
Pre-Tax Income (MRY)
-72,296,000
Normalized Pre-Tax Income (MRY)
-72,296,000
Income after Taxes (MRY)
-71,798,000
Income from Continuous Operations (MRY)
-71,798,000
Consolidated Net Income/Loss (MRY)
-71,798,000
Normalized Income after Taxes (MRY)
-71,798,000
EBIT (MRY)
-80,823,000
EBITDA (MRY)
-79,422,000
Balance Sheet Financials
Current Assets (MRQ)
491,681,000
Property, Plant, and Equipment (MRQ)
4,316,000
Long-Term Assets (MRQ)
114,972,000
Total Assets (MRQ)
606,653,000
Current Liabilities (MRQ)
75,282,000
Long-Term Debt (MRQ)
Long-Term Liabilities (MRQ)
142,640,000
Total Liabilities (MRQ)
217,922,000
Common Equity (MRQ)
388,731,000
Tangible Shareholders Equity (MRQ)
388,731,000
Shareholders Equity (MRQ)
388,731,000
Common Shares Outstanding (MRQ)
44,639,000
Cash Flow Statement Financials
Cash Flow from Operating Activities (MRY)
-67,470,000
Cash Flow from Investing Activities (MRY)
-160,598,000
Cash Flow from Financial Activities (MRY)
377,781,000
Beginning Cash (MRY)
89,388,000
End Cash (MRY)
239,101,000
Increase/Decrease in Cash (MRY)
149,713,000
Fundamental Ratios
PE Ratio (Current Year Earnings Estimate)
PE Ratio (Trailing 12 Months)
PEG Ratio (Long Term Growth Estimate)
Price to Sales Ratio (Trailing 12 Months)
53.92
Price to Book Ratio (Most Recent Quarterly Book Value per Share)
3.05
Price to Cash Ratio (Most Recent Annual Cash Flow per Share)
Pre-Tax Margin (Trailing 12 Months)
-267.49
Net Margin (Trailing 12 Months)
-266.77
Return on Equity (Trailing 12 Months)
-17.98
Return on Assets (Trailing 12 Months)
-14.91
Current Ratio (Most Recent Fiscal Quarter)
6.53
Quick Ratio (Most Recent Fiscal Quarter)
6.53
Debt to Common Equity (Most Recent Fiscal Quarter)
0.00
Inventory Turnover (Trailing 12 Months)
Book Value per Share (Most Recent Fiscal Quarter)
9.46
Earnings
Fiscal Period End, Next Quarterly Earnings Report
2025-12-31
Quarterly Earnings per Share Estimate
-0.20
Next Expected Quarterly Earnings Report Date
2026-03-26
Days Until Next Expected Quarterly Earnings Report
111
Fiscal Period End, Last Quarterly Earnings Report
2025-09-30
Last Quarterly Earnings per Share Estimate
0.19
Last Quarterly Earnings per Share
-0.09
Last Quarterly Earnings Report Date
2025-11-10
Days Since Last Quarterly Earnings Report
25
Earnings per Share (Most Recent Fiscal Year)
-7.26
Diluted Earnings per Share (Trailing 12 Months)
-1.51
Dividends
Last Dividend Date
Last Dividend Amount
Days Since Last Dividend
Annual Dividend (Based on Last Quarter)
0.00
Dividend Yield (Based on Last Quarter)
0.00
Percent Growth in Revenue/Net Income
Percent Growth in Quarterly Revenue (QoQ)
17,963.03
Percent Growth in Quarterly Revenue (YoY)
12,113.07
Percent Growth in Annual Revenue
611.92
Percent Growth in Quarterly Net Income (QoQ)
132.91
Percent Growth in Quarterly Net Income (YoY)
139.82
Percent Growth in Annual Net Income
-12,762.79
New High/Low in Revenue/Net Income
New 5-Year High Annual Revenue
True
New 5-Year Low Annual Revenue
False
New 5-Year High Quarterly Revenue (QoQ)
True
New 5-Year Low Quarterly Revenue (QoQ)
False
New 5-Year High Quarterly Revenue (YoY)
True
New 5-Year Low Quarterly Revenue (YoY)
False
New 5-Year High Annual Net Income
False
New 5-Year Low Annual Net Income
True
New 5-Year High Quarterly Net Income (QoQ)
True
New 5-Year Low Quarterly Net Income (QoQ)
False
New 5-Year High Quarterly Net Income (YoY)
True
New 5-Year Low Quarterly Net Income (YoY)
False
Consecutive Quarters/Years of Increasing/Decreasing Revenue/Net Income
Consecutive Quarters of Increasing Revenue (QoQ)
1
Consecutive Quarters of Decreasing Revenue (QoQ)
0
Consecutive Quarters of Increasing Revenue (YoY)
1
Consecutive Quarters of Decreasing Revenue (YoY)
0
Consecutive Years of Increasing Revenue
1
Consecutive Years of Decreasing Revenue
0
Consecutive Quarters of Increasing Net Income (QoQ)
1
Consecutive Quarters of Decreasing Net Income (QoQ)
0
Consecutive Quarters of Increasing Net Income (YoY)
1
Consecutive Quarters of Decreasing Net Income (YoY)
0
Consecutive Years of Increasing Net Income
0
Consecutive Years of Decreasing Net Income
1
Splits
Last Split Date (if within past year)
Last Split Ratio (if within past year)
Days Since Last Split (if within past year)
Volatility Metrics
Historical Volatility (Close-to-Close) (10-Day)
0.5987
Historical Volatility (Close-to-Close) (20-Day)
0.8667
Historical Volatility (Close-to-Close) (30-Day)
0.9644
Historical Volatility (Close-to-Close) (60-Day)
0.7635
Historical Volatility (Close-to-Close) (90-Day)
0.6949
Historical Volatility (Close-to-Close) (120-Day)
0.6743
Historical Volatility (Close-to-Close) (150-Day)
0.6467
Historical Volatility (Close-to-Close) (180-Day)
0.6171
Historical Volatility (Parkinson) (10-Day)
0.6469
Historical Volatility (Parkinson) (20-Day)
0.7283
Historical Volatility (Parkinson) (30-Day)
0.7879
Historical Volatility (Parkinson) (60-Day)
0.7224
Historical Volatility (Parkinson) (90-Day)
0.6695
Historical Volatility (Parkinson) (120-Day)
0.6472
Historical Volatility (Parkinson) (150-Day)
0.6135
Historical Volatility (Parkinson) (180-Day)
0.6047
Implied Volatility (Calls) (10-Day)
0.7625
Implied Volatility (Calls) (20-Day)
0.7511
Implied Volatility (Calls) (30-Day)
0.7283
Implied Volatility (Calls) (60-Day)
0.7015
Implied Volatility (Calls) (90-Day)
0.7064
Implied Volatility (Calls) (120-Day)
0.7112
Implied Volatility (Calls) (150-Day)
0.7183
Implied Volatility (Calls) (180-Day)
0.7273
Implied Volatility (Puts) (10-Day)
0.7702
Implied Volatility (Puts) (20-Day)
0.7574
Implied Volatility (Puts) (30-Day)
0.7318
Implied Volatility (Puts) (60-Day)
0.7002
Implied Volatility (Puts) (90-Day)
0.7031
Implied Volatility (Puts) (120-Day)
0.7062
Implied Volatility (Puts) (150-Day)
0.7105
Implied Volatility (Puts) (180-Day)
0.7158
Implied Volatility (Mean) (10-Day)
0.7663
Implied Volatility (Mean) (20-Day)
0.7542
Implied Volatility (Mean) (30-Day)
0.7300
Implied Volatility (Mean) (60-Day)
0.7008
Implied Volatility (Mean) (90-Day)
0.7048
Implied Volatility (Mean) (120-Day)
0.7087
Implied Volatility (Mean) (150-Day)
0.7144
Implied Volatility (Mean) (180-Day)
0.7216
Put-Call Implied Volatility Ratio (10-Day)
1.0101
Put-Call Implied Volatility Ratio (20-Day)
1.0084
Put-Call Implied Volatility Ratio (30-Day)
1.0049
Put-Call Implied Volatility Ratio (60-Day)
0.9981
Put-Call Implied Volatility Ratio (90-Day)
0.9953
Put-Call Implied Volatility Ratio (120-Day)
0.9929
Put-Call Implied Volatility Ratio (150-Day)
0.9890
Put-Call Implied Volatility Ratio (180-Day)
0.9841
Implied Volatility Skew (10-Day)
-0.0087
Implied Volatility Skew (20-Day)
0.0176
Implied Volatility Skew (30-Day)
0.0704
Implied Volatility Skew (60-Day)
0.1131
Implied Volatility Skew (90-Day)
0.0675
Implied Volatility Skew (120-Day)
0.0218
Implied Volatility Skew (150-Day)
0.0012
Implied Volatility Skew (180-Day)
0.0025
Option Statistics
Put-Call Ratio (Volume) (10-Day)
Put-Call Ratio (Volume) (20-Day)
1.6667
Put-Call Ratio (Volume) (30-Day)
1.6667
Put-Call Ratio (Volume) (60-Day)
1.6667
Put-Call Ratio (Volume) (90-Day)
1.6667
Put-Call Ratio (Volume) (120-Day)
1.6667
Put-Call Ratio (Volume) (150-Day)
Put-Call Ratio (Volume) (180-Day)
Put-Call Ratio (Open Interest) (10-Day)
4.8182
Put-Call Ratio (Open Interest) (20-Day)
4.5369
Put-Call Ratio (Open Interest) (30-Day)
3.9742
Put-Call Ratio (Open Interest) (60-Day)
2.6552
Put-Call Ratio (Open Interest) (90-Day)
1.6183
Put-Call Ratio (Open Interest) (120-Day)
0.5813
Put-Call Ratio (Open Interest) (150-Day)
0.0803
Put-Call Ratio (Open Interest) (180-Day)
0.0482
Percentiles Within Industry of Price Performance
Percentile Within Industry, Percent Change in Price, Past 52 Weeks
55.59
Percentile Within Industry, Percent Change in Price, Past 26 Weeks
86.81
Percentile Within Industry, Percent Change in Price, Past 13 Weeks
87.15
Percentile Within Industry, Percent Change in Price, Past 4 Weeks
88.98
Percentile Within Industry, Percent Change in Price, Past 2 Weeks
56.93
Percentile Within Industry, Percent Change in Price, Past Week
13.02
Percentile Within Industry, Percent Change in Price, 1 Day
10.85
Percentiles Within Industry of Revenue/Net Income Growth
Percentile Within Industry, Percent Growth in Quarterly Revenue (QoQ)
99.23
Percentile Within Industry, Percent Growth in Quarterly Revenue (YoY)
98.79
Percentile Within Industry, Percent Growth in Annual Revenue
92.86
Percentile Within Industry, Percent Growth in Quarterly Net Income (QoQ)
93.53
Percentile Within Industry, Percent Growth in Quarterly Net Income (YoY)
94.28
Percentile Within Industry, Percent Growth in Annual Net Income
0.17
Percentiles Within Industry of Fundamental Ratios and Percentages
Percentile Within Industry, PE Ratio (Current Year Earnings Estimate)
Percentile Within Industry, PE Ratio (Trailing 12 Months)
Percentile Within Industry, PEG Ratio (Long Term Growth Estimate)
Percentile Within Industry, Price to Sales Ratio (Trailing 12 Months)
81.85
Percentile Within Industry, Price to Book Ratio (Most Recent Quarterly Book Value per Share)
54.13
Percentile Within Industry, Price to Cash Ratio (Most Recent Annual Cash Flow per Share)
Percentile Within Industry, Pre-Tax Margin (Trailing 12 Months)
55.52
Percentile Within Industry, Net Margin (Trailing 12 Months)
43.37
Percentile Within Industry, Return on Equity (Trailing 12 Months)
85.83
Percentile Within Industry, Return on Assets (Trailing 12 Months)
84.32
Percentile Within Industry, Current Ratio (Most Recent Fiscal Quarter)
62.91
Percentile Within Industry, Quick Ratio (Most Recent Fiscal Quarter)
63.40
Percentile Within Industry, Debt to Common Equity (Most Recent Fiscal Quarter)
71.29
Percentile Within Industry, Inventory Turnover (Trailing 12 Months)
Percentile Within Industry, Dividend Yield (Based on Last Quarter)
99.33
Percentile Within Industry, Percentage Held By Insiders (Latest Annual Proxy Report)
26.34
Percentile Within Industry, Percentage Held By Institutions (Latest 13F Reports)
Percentiles Within Sector of Price Performance
Percentile Within Sector, Percent Change in Price, Past 52 Weeks
58.65
Percentile Within Sector, Percent Change in Price, Past 26 Weeks
91.07
Percentile Within Sector, Percent Change in Price, Past 13 Weeks
90.79
Percentile Within Sector, Percent Change in Price, Past 4 Weeks
91.26
Percentile Within Sector, Percent Change in Price, Past 2 Weeks
59.21
Percentile Within Sector, Percent Change in Price, Past Week
10.15
Percentile Within Sector, Percent Change in Price, 1 Day
12.78
Percentiles Within Sector of Revenue/Net Income Growth
Percentile Within Sector, Percent Growth in Quarterly Revenue (QoQ)
99.69
Percentile Within Sector, Percent Growth in Quarterly Revenue (YoY)
99.53
Percentile Within Sector, Percent Growth in Annual Revenue
96.64
Percentile Within Sector, Percent Growth in Quarterly Net Income (QoQ)
93.33
Percentile Within Sector, Percent Growth in Quarterly Net Income (YoY)
93.16
Percentile Within Sector, Percent Growth in Annual Net Income
0.19
Percentiles Within Sector of Fundamental Ratios and Percentages
Percentile Within Sector, PE Ratio (Current Year Earnings Estimate)
Percentile Within Sector, PE Ratio (Trailing 12 Months)
Percentile Within Sector, PEG Ratio (Long Term Growth Estimate)
Percentile Within Sector, Price to Sales Ratio (Trailing 12 Months)
90.88
Percentile Within Sector, Price to Book Ratio (Most Recent Quarterly Book Value per Share)
56.14
Percentile Within Sector, Price to Cash Ratio (Most Recent Annual Cash Flow per Share)
Percentile Within Sector, Pre-Tax Margin (Trailing 12 Months)
32.66
Percentile Within Sector, Net Margin (Trailing 12 Months)
23.59
Percentile Within Sector, Return on Equity (Trailing 12 Months)
66.70
Percentile Within Sector, Return on Assets (Trailing 12 Months)
63.49
Percentile Within Sector, Current Ratio (Most Recent Fiscal Quarter)
74.37
Percentile Within Sector, Quick Ratio (Most Recent Fiscal Quarter)
75.62
Percentile Within Sector, Debt to Common Equity (Most Recent Fiscal Quarter)
55.28
Percentile Within Sector, Inventory Turnover (Trailing 12 Months)
Percentile Within Sector, Dividend Yield (Based on Last Quarter)
93.03
Percentile Within Sector, Percentage Held By Insiders (Latest Annual Proxy Report)
34.09
Percentile Within Sector, Percentage Held By Institutions (Latest 13F Reports)
Percentiles Within Market of Price Performance
Percentile Within Market, Percent Change in Price, Past 52 Weeks
46.57
Percentile Within Market, Percent Change in Price, Past 26 Weeks
97.83
Percentile Within Market, Percent Change in Price, Past 13 Weeks
97.99
Percentile Within Market, Percent Change in Price, Past 4 Weeks
97.94
Percentile Within Market, Percent Change in Price, Past 2 Weeks
76.50
Percentile Within Market, Percent Change in Price, Past Week
2.98
Percentile Within Market, Percent Change in Price, 1 Day
10.39
Percentiles Within Market of Revenue/Net Income Growth
Percentile Within Market, Percent Growth in Quarterly Revenue (QoQ)
99.90
Percentile Within Market, Percent Growth in Quarterly Revenue (YoY)
99.83
Percentile Within Market, Percent Growth in Annual Revenue
99.16
Percentile Within Market, Percent Growth in Quarterly Net Income (QoQ)
89.19
Percentile Within Market, Percent Growth in Quarterly Net Income (YoY)
87.51
Percentile Within Market, Percent Growth in Annual Net Income
0.26
Percentiles Within Market of Fundamental Ratios and Percentages
Percentile Within Market, PE Ratio (Current Year Earnings Estimate)
Percentile Within Market, PE Ratio (Trailing 12 Months)
Percentile Within Market, PEG Ratio (Long Term Growth Estimate)
Percentile Within Market, Price to Sales Ratio (Trailing 12 Months)
97.02
Percentile Within Market, Price to Book Ratio (Most Recent Quarterly Book Value per Share)
66.95
Percentile Within Market, Price to Cash Ratio (Most Recent Annual Cash Flow per Share)
Percentile Within Market, Pre-Tax Margin (Trailing 12 Months)
8.96
Percentile Within Market, Net Margin (Trailing 12 Months)
6.34
Percentile Within Market, Return on Equity (Trailing 12 Months)
26.39
Percentile Within Market, Return on Assets (Trailing 12 Months)
22.31
Percentile Within Market, Current Ratio (Most Recent Fiscal Quarter)
88.95
Percentile Within Market, Quick Ratio (Most Recent Fiscal Quarter)
89.95
Percentile Within Market, Debt to Common Equity (Most Recent Fiscal Quarter)
31.14
Percentile Within Market, Inventory Turnover (Trailing 12 Months)
Percentile Within Market, Dividend Yield (Based on Last Quarter)
61.83
Percentile Within Market, Percentage Held By Insiders (Latest Annual Proxy Report)
45.61
Percentile Within Market, Percentage Held By Institutions (Latest 13F Reports)