Septerna, Inc. (SEPN)

Last Closing Price: 24.09 (2025-10-13)

Profile
Ticker
SEPN
Security Name
Septerna, Inc.
Exchange
NASDAQ
Sector
Healthcare
Industry
Biotechnology
Free Float
42,668,000
Market Capitalization
1,031,700,000
Average Volume (Last 20 Days)
322,097
Beta (Past 60 Months)
Percentage Held By Insiders (Latest Annual Proxy Report)
4.30
Percentage Held By Institutions (Latest 13F Reports)
Recent Price/Volume
Closing Price
23.07
Opening Price
21.93
High Price
23.27
Low Price
20.71
Volume
535,000
Previous Closing Price
23.14
Previous Opening Price
22.45
Previous High Price
23.61
Previous Low Price
22.30
Previous Volume
410,000
High/Low Price
52-Week High Price
28.99
26-Week High Price
23.61
13-Week High Price
23.61
4-Week High Price
23.61
2-Week High Price
23.61
1-Week High Price
23.61
52-Week Low Price
4.17
26-Week Low Price
5.51
13-Week Low Price
10.62
4-Week Low Price
14.00
2-Week Low Price
17.33
1-Week Low Price
20.18
High/Low Volume
52-Week High Volume
37,815,761
26-Week High Volume
37,815,761
13-Week High Volume
798,000
4-Week High Volume
654,000
2-Week High Volume
537,000
1-Week High Volume
537,000
52-Week Low Volume
58,094
26-Week Low Volume
104,000
13-Week Low Volume
104,000
4-Week Low Volume
119,000
2-Week Low Volume
277,000
1-Week Low Volume
410,000
Money Flow
Total Money Flow, Past 52 Weeks
1,607,983,700
Total Money Flow, Past 26 Weeks
920,167,329
Total Money Flow, Past 13 Weeks
255,312,829
Total Money Flow, Past 4 Weeks
126,775,376
Total Money Flow, Past 2 Weeks
90,741,699
Total Money Flow, Past Week
53,908,423
Total Money Flow, 1 Day
11,958,142
Total Volume
Total Volume, Past 52 Weeks
135,782,055
Total Volume, Past 26 Weeks
84,294,589
Total Volume, Past 13 Weeks
16,881,000
Total Volume, Past 4 Weeks
6,676,000
Total Volume, Past 2 Weeks
4,389,000
Total Volume, Past Week
2,468,000
Percent Change in Price
Percent Change in Price, Past 52 Weeks
7.80
Percent Change in Price, Past 26 Weeks
303.32
Percent Change in Price, Past 13 Weeks
96.68
Percent Change in Price, Past 4 Weeks
61.55
Percent Change in Price, Past 2 Weeks
32.21
Percent Change in Price, Past Week
11.56
Percent Change in Price, 1 Day
-0.30
New High/Low in Price
Reached New 52-Week High Price
False
Reached New 26-Week High Price
False
Reached New 13-Week High Price
False
Reached New 4-Week High Price
False
Reached New 2-Week High Price
False
Reached New 1-Week High Price
False
Reached New 52-Week Low Price
False
Reached New 26-Week Low Price
False
Reached New 13-Week Low Price
False
Reached New 4-Week Low Price
False
Reached New 2-Week Low Price
False
Reached New 1-Week Low Price
False
Consecutive Days/Weeks of Increasing/Decreasing Price
Consecutive Days of Increasing Price
0
Consecutive Weeks of Increasing Price
4
Consecutive Days of Decreasing Price
1
Consecutive Weeks of Decreasing Price
0
Consecutive Days/Weeks of Increasing/Decreasing Volume
Consecutive Days of Increasing Volume
1
Consecutive Weeks of Increasing Volume
3
Consecutive Days of Decreasing Volume
0
Consecutive Weeks of Decreasing Volume
0
New High/Low in Volume
Had New 52-Week High Volume
False
Had New 26-Week High Volume
False
Had New 13-Week High Volume
False
Had New 4-Week High Volume
False
Had New 2-Week High Volume
False
Had New 1-Week High Volume
False
Had New 52-Week Low Volume
False
Had New 26-Week Low Volume
False
Had New 13-Week Low Volume
False
Had New 4-Week Low Volume
False
Had New 2-Week Low Volume
False
Had New 1-Week Low Volume
False
Moving Averages
Simple Moving Average (5-Day)
22.10
Simple Moving Average (10-Day)
20.73
Simple Moving Average (20-Day)
18.27
Simple Moving Average (50-Day)
14.83
Simple Moving Average (100-Day)
12.93
Simple Moving Average (200-Day)
11.78
Previous Simple Moving Average (5-Day)
21.62
Previous Simple Moving Average (10-Day)
20.17
Previous Simple Moving Average (20-Day)
17.83
Previous Simple Moving Average (50-Day)
14.61
Previous Simple Moving Average (100-Day)
12.80
Previous Simple Moving Average (200-Day)
11.79
Technical Indicators
MACD (12, 26, 9)
2.30
MACD (12, 26, 9) Signal
1.86
Previous MACD (12, 26, 9)
2.21
Previous MACD (12, 26, 9) Signal
1.75
RSI (14-Day)
90.39
Previous RSI (14-Day)
91.34
Stochastic (14, 3, 3) %K
93.09
Stochastic (14, 3, 3) %D
91.33
Previous Stochastic (14, 3, 3) %K
91.75
Previous Stochastic (14, 3, 3) %D
90.49
Upper Bollinger Band (20, 2)
23.92
Lower Bollinger Band (20, 2)
12.62
Previous Upper Bollinger Band (20, 2)
23.29
Previous Lower Bollinger Band (20, 2)
12.38
Income Statement Financials
Quarterly Revenue (MRQ)
119,000
Quarterly Net Income (MRQ)
-24,838,000
Previous Quarterly Revenue (QoQ)
219,000
Previous Quarterly Revenue (YoY)
370,000
Previous Quarterly Net Income (QoQ)
-21,476,000
Previous Quarterly Net Income (YoY)
-16,441,000
Revenue (MRY)
1,075,000
Net Income (MRY)
-71,798,000
Previous Annual Revenue
151,000
Previous Net Income
567,000
Cost of Goods Sold (MRY)
Gross Profit (MRY)
1,075,000
Operating Expenses (MRY)
81,898,000
Operating Income (MRY)
-80,823,000
Non-Operating Income/Expense (MRY)
8,527,000
Pre-Tax Income (MRY)
-72,296,000
Normalized Pre-Tax Income (MRY)
-72,296,000
Income after Taxes (MRY)
-71,798,000
Income from Continuous Operations (MRY)
-71,798,000
Consolidated Net Income/Loss (MRY)
-71,798,000
Normalized Income after Taxes (MRY)
-71,798,000
EBIT (MRY)
-80,823,000
EBITDA (MRY)
-79,422,000
Balance Sheet Financials
Current Assets (MRQ)
334,141,000
Property, Plant, and Equipment (MRQ)
4,688,000
Long-Term Assets (MRQ)
81,090,000
Total Assets (MRQ)
415,231,000
Current Liabilities (MRQ)
15,127,000
Long-Term Debt (MRQ)
Long-Term Liabilities (MRQ)
22,547,000
Total Liabilities (MRQ)
37,674,000
Common Equity (MRQ)
377,557,000
Tangible Shareholders Equity (MRQ)
377,557,000
Shareholders Equity (MRQ)
377,557,000
Common Shares Outstanding (MRQ)
44,568,000
Cash Flow Statement Financials
Cash Flow from Operating Activities (MRY)
-67,470,000
Cash Flow from Investing Activities (MRY)
-160,598,000
Cash Flow from Financial Activities (MRY)
377,781,000
Beginning Cash (MRY)
89,388,000
End Cash (MRY)
239,101,000
Increase/Decrease in Cash (MRY)
149,713,000
Fundamental Ratios
PE Ratio (Current Year Earnings Estimate)
PE Ratio (Trailing 12 Months)
PEG Ratio (Long Term Growth Estimate)
Price to Sales Ratio (Trailing 12 Months)
1,421.07
Price to Book Ratio (Most Recent Quarterly Book Value per Share)
2.73
Price to Cash Ratio (Most Recent Annual Cash Flow per Share)
Pre-Tax Margin (Trailing 12 Months)
-12,093.80
Net Margin (Trailing 12 Months)
-12,053.03
Return on Equity (Trailing 12 Months)
-31.52
Return on Assets (Trailing 12 Months)
-23.65
Current Ratio (Most Recent Fiscal Quarter)
22.09
Quick Ratio (Most Recent Fiscal Quarter)
22.09
Debt to Common Equity (Most Recent Fiscal Quarter)
0.00
Inventory Turnover (Trailing 12 Months)
Book Value per Share (Most Recent Fiscal Quarter)
9.46
Earnings
Fiscal Period End, Next Quarterly Earnings Report
2025-09-30
Quarterly Earnings per Share Estimate
0.19
Next Expected Quarterly Earnings Report Date
2025-11-19
Days Until Next Expected Quarterly Earnings Report
39
Fiscal Period End, Last Quarterly Earnings Report
2025-06-30
Last Quarterly Earnings per Share Estimate
-0.05
Last Quarterly Earnings per Share
-0.56
Last Quarterly Earnings Report Date
2025-08-11
Days Since Last Quarterly Earnings Report
61
Earnings per Share (Most Recent Fiscal Year)
-7.26
Diluted Earnings per Share (Trailing 12 Months)
-10.09
Dividends
Last Dividend Date
Last Dividend Amount
Days Since Last Dividend
Annual Dividend (Based on Last Quarter)
0.00
Dividend Yield (Based on Last Quarter)
0.00
Percent Growth in Revenue/Net Income
Percent Growth in Quarterly Revenue (QoQ)
-45.66
Percent Growth in Quarterly Revenue (YoY)
-67.84
Percent Growth in Annual Revenue
611.92
Percent Growth in Quarterly Net Income (QoQ)
-15.65
Percent Growth in Quarterly Net Income (YoY)
-51.07
Percent Growth in Annual Net Income
-12,762.79
New High/Low in Revenue/Net Income
New 5-Year High Annual Revenue
True
New 5-Year Low Annual Revenue
False
New 5-Year High Quarterly Revenue (QoQ)
False
New 5-Year Low Quarterly Revenue (QoQ)
False
New 5-Year High Quarterly Revenue (YoY)
False
New 5-Year Low Quarterly Revenue (YoY)
True
New 5-Year High Annual Net Income
False
New 5-Year Low Annual Net Income
True
New 5-Year High Quarterly Net Income (QoQ)
False
New 5-Year Low Quarterly Net Income (QoQ)
True
New 5-Year High Quarterly Net Income (YoY)
False
New 5-Year Low Quarterly Net Income (YoY)
True
Consecutive Quarters/Years of Increasing/Decreasing Revenue/Net Income
Consecutive Quarters of Increasing Revenue (QoQ)
0
Consecutive Quarters of Decreasing Revenue (QoQ)
1
Consecutive Quarters of Increasing Revenue (YoY)
0
Consecutive Quarters of Decreasing Revenue (YoY)
2
Consecutive Years of Increasing Revenue
1
Consecutive Years of Decreasing Revenue
0
Consecutive Quarters of Increasing Net Income (QoQ)
0
Consecutive Quarters of Decreasing Net Income (QoQ)
5
Consecutive Quarters of Increasing Net Income (YoY)
0
Consecutive Quarters of Decreasing Net Income (YoY)
3
Consecutive Years of Increasing Net Income
0
Consecutive Years of Decreasing Net Income
1
Splits
Last Split Date (if within past year)
Last Split Ratio (if within past year)
Days Since Last Split (if within past year)
Volatility Metrics
Historical Volatility (Close-to-Close) (10-Day)
0.4073
Historical Volatility (Close-to-Close) (20-Day)
0.3690
Historical Volatility (Close-to-Close) (30-Day)
0.4858
Historical Volatility (Close-to-Close) (60-Day)
0.5635
Historical Volatility (Close-to-Close) (90-Day)
0.5603
Historical Volatility (Close-to-Close) (120-Day)
0.5360
Historical Volatility (Close-to-Close) (150-Day)
0.8291
Historical Volatility (Close-to-Close) (180-Day)
0.8139
Historical Volatility (Parkinson) (10-Day)
0.7909
Historical Volatility (Parkinson) (20-Day)
0.6714
Historical Volatility (Parkinson) (30-Day)
0.6281
Historical Volatility (Parkinson) (60-Day)
0.6110
Historical Volatility (Parkinson) (90-Day)
0.5663
Historical Volatility (Parkinson) (120-Day)
0.5606
Historical Volatility (Parkinson) (150-Day)
0.6587
Historical Volatility (Parkinson) (180-Day)
0.6685
Implied Volatility (Calls) (10-Day)
0.8148
Implied Volatility (Calls) (20-Day)
0.8380
Implied Volatility (Calls) (30-Day)
0.8612
Implied Volatility (Calls) (60-Day)
0.8582
Implied Volatility (Calls) (90-Day)
0.8068
Implied Volatility (Calls) (120-Day)
0.7876
Implied Volatility (Calls) (150-Day)
0.7795
Implied Volatility (Calls) (180-Day)
0.7717
Implied Volatility (Puts) (10-Day)
0.7910
Implied Volatility (Puts) (20-Day)
0.8096
Implied Volatility (Puts) (30-Day)
0.8283
Implied Volatility (Puts) (60-Day)
0.8241
Implied Volatility (Puts) (90-Day)
0.7799
Implied Volatility (Puts) (120-Day)
0.7654
Implied Volatility (Puts) (150-Day)
0.7626
Implied Volatility (Puts) (180-Day)
0.7592
Implied Volatility (Mean) (10-Day)
0.8029
Implied Volatility (Mean) (20-Day)
0.8238
Implied Volatility (Mean) (30-Day)
0.8448
Implied Volatility (Mean) (60-Day)
0.8412
Implied Volatility (Mean) (90-Day)
0.7933
Implied Volatility (Mean) (120-Day)
0.7765
Implied Volatility (Mean) (150-Day)
0.7710
Implied Volatility (Mean) (180-Day)
0.7655
Put-Call Implied Volatility Ratio (10-Day)
0.9708
Put-Call Implied Volatility Ratio (20-Day)
0.9661
Put-Call Implied Volatility Ratio (30-Day)
0.9618
Put-Call Implied Volatility Ratio (60-Day)
0.9603
Put-Call Implied Volatility Ratio (90-Day)
0.9666
Put-Call Implied Volatility Ratio (120-Day)
0.9718
Put-Call Implied Volatility Ratio (150-Day)
0.9783
Put-Call Implied Volatility Ratio (180-Day)
0.9838
Implied Volatility Skew (10-Day)
0.1501
Implied Volatility Skew (20-Day)
0.1057
Implied Volatility Skew (30-Day)
0.0614
Implied Volatility Skew (60-Day)
0.0015
Implied Volatility Skew (90-Day)
-0.0097
Implied Volatility Skew (120-Day)
-0.0076
Implied Volatility Skew (150-Day)
-0.0011
Implied Volatility Skew (180-Day)
0.0056
Option Statistics
Put-Call Ratio (Volume) (10-Day)
6.4857
Put-Call Ratio (Volume) (20-Day)
4.7714
Put-Call Ratio (Volume) (30-Day)
3.0571
Put-Call Ratio (Volume) (60-Day)
0.6786
Put-Call Ratio (Volume) (90-Day)
0.1429
Put-Call Ratio (Volume) (120-Day)
0.0000
Put-Call Ratio (Volume) (150-Day)
0.0000
Put-Call Ratio (Volume) (180-Day)
0.0000
Put-Call Ratio (Open Interest) (10-Day)
10.3610
Put-Call Ratio (Open Interest) (20-Day)
7.1266
Put-Call Ratio (Open Interest) (30-Day)
3.8921
Put-Call Ratio (Open Interest) (60-Day)
1.1114
Put-Call Ratio (Open Interest) (90-Day)
2.9460
Put-Call Ratio (Open Interest) (120-Day)
2.6380
Put-Call Ratio (Open Interest) (150-Day)
1.5508
Put-Call Ratio (Open Interest) (180-Day)
0.4636
Percentiles Within Industry of Price Performance
Percentile Within Industry, Percent Change in Price, Past 52 Weeks
62.10
Percentile Within Industry, Percent Change in Price, Past 26 Weeks
95.32
Percentile Within Industry, Percent Change in Price, Past 13 Weeks
91.29
Percentile Within Industry, Percent Change in Price, Past 4 Weeks
93.87
Percentile Within Industry, Percent Change in Price, Past 2 Weeks
92.10
Percentile Within Industry, Percent Change in Price, Past Week
86.13
Percentile Within Industry, Percent Change in Price, 1 Day
88.06
Percentiles Within Industry of Revenue/Net Income Growth
Percentile Within Industry, Percent Growth in Quarterly Revenue (QoQ)
14.94
Percentile Within Industry, Percent Growth in Quarterly Revenue (YoY)
13.65
Percentile Within Industry, Percent Growth in Annual Revenue
93.11
Percentile Within Industry, Percent Growth in Quarterly Net Income (QoQ)
36.38
Percentile Within Industry, Percent Growth in Quarterly Net Income (YoY)
29.76
Percentile Within Industry, Percent Growth in Annual Net Income
0.16
Percentiles Within Industry of Fundamental Ratios and Percentages
Percentile Within Industry, PE Ratio (Current Year Earnings Estimate)
Percentile Within Industry, PE Ratio (Trailing 12 Months)
Percentile Within Industry, PEG Ratio (Long Term Growth Estimate)
Percentile Within Industry, Price to Sales Ratio (Trailing 12 Months)
98.11
Percentile Within Industry, Price to Book Ratio (Most Recent Quarterly Book Value per Share)
50.95
Percentile Within Industry, Price to Cash Ratio (Most Recent Annual Cash Flow per Share)
Percentile Within Industry, Pre-Tax Margin (Trailing 12 Months)
10.51
Percentile Within Industry, Net Margin (Trailing 12 Months)
4.51
Percentile Within Industry, Return on Equity (Trailing 12 Months)
76.31
Percentile Within Industry, Return on Assets (Trailing 12 Months)
76.96
Percentile Within Industry, Current Ratio (Most Recent Fiscal Quarter)
94.20
Percentile Within Industry, Quick Ratio (Most Recent Fiscal Quarter)
94.26
Percentile Within Industry, Debt to Common Equity (Most Recent Fiscal Quarter)
72.16
Percentile Within Industry, Inventory Turnover (Trailing 12 Months)
Percentile Within Industry, Dividend Yield (Based on Last Quarter)
99.35
Percentile Within Industry, Percentage Held By Insiders (Latest Annual Proxy Report)
25.71
Percentile Within Industry, Percentage Held By Institutions (Latest 13F Reports)
Percentiles Within Sector of Price Performance
Percentile Within Sector, Percent Change in Price, Past 52 Weeks
63.59
Percentile Within Sector, Percent Change in Price, Past 26 Weeks
96.77
Percentile Within Sector, Percent Change in Price, Past 13 Weeks
93.55
Percentile Within Sector, Percent Change in Price, Past 4 Weeks
95.48
Percentile Within Sector, Percent Change in Price, Past 2 Weeks
94.01
Percentile Within Sector, Percent Change in Price, Past Week
89.95
Percentile Within Sector, Percent Change in Price, 1 Day
88.48
Percentiles Within Sector of Revenue/Net Income Growth
Percentile Within Sector, Percent Growth in Quarterly Revenue (QoQ)
7.62
Percentile Within Sector, Percent Growth in Quarterly Revenue (YoY)
6.40
Percentile Within Sector, Percent Growth in Annual Revenue
96.69
Percentile Within Sector, Percent Growth in Quarterly Net Income (QoQ)
35.73
Percentile Within Sector, Percent Growth in Quarterly Net Income (YoY)
26.73
Percentile Within Sector, Percent Growth in Annual Net Income
0.19
Percentiles Within Sector of Fundamental Ratios and Percentages
Percentile Within Sector, PE Ratio (Current Year Earnings Estimate)
Percentile Within Sector, PE Ratio (Trailing 12 Months)
Percentile Within Sector, PEG Ratio (Long Term Growth Estimate)
Percentile Within Sector, Price to Sales Ratio (Trailing 12 Months)
99.23
Percentile Within Sector, Price to Book Ratio (Most Recent Quarterly Book Value per Share)
51.96
Percentile Within Sector, Price to Cash Ratio (Most Recent Annual Cash Flow per Share)
Percentile Within Sector, Pre-Tax Margin (Trailing 12 Months)
6.03
Percentile Within Sector, Net Margin (Trailing 12 Months)
1.90
Percentile Within Sector, Return on Equity (Trailing 12 Months)
58.29
Percentile Within Sector, Return on Assets (Trailing 12 Months)
56.87
Percentile Within Sector, Current Ratio (Most Recent Fiscal Quarter)
96.36
Percentile Within Sector, Quick Ratio (Most Recent Fiscal Quarter)
96.41
Percentile Within Sector, Debt to Common Equity (Most Recent Fiscal Quarter)
55.89
Percentile Within Sector, Inventory Turnover (Trailing 12 Months)
Percentile Within Sector, Dividend Yield (Based on Last Quarter)
93.07
Percentile Within Sector, Percentage Held By Insiders (Latest Annual Proxy Report)
33.53
Percentile Within Sector, Percentage Held By Institutions (Latest 13F Reports)
Percentiles Within Market of Price Performance
Percentile Within Market, Percent Change in Price, Past 52 Weeks
58.06
Percentile Within Market, Percent Change in Price, Past 26 Weeks
98.67
Percentile Within Market, Percent Change in Price, Past 13 Weeks
97.80
Percentile Within Market, Percent Change in Price, Past 4 Weeks
98.57
Percentile Within Market, Percent Change in Price, Past 2 Weeks
98.22
Percentile Within Market, Percent Change in Price, Past Week
96.91
Percentile Within Market, Percent Change in Price, 1 Day
80.98
Percentiles Within Market of Revenue/Net Income Growth
Percentile Within Market, Percent Growth in Quarterly Revenue (QoQ)
3.06
Percentile Within Market, Percent Growth in Quarterly Revenue (YoY)
1.56
Percentile Within Market, Percent Growth in Annual Revenue
99.17
Percentile Within Market, Percent Growth in Quarterly Net Income (QoQ)
31.67
Percentile Within Market, Percent Growth in Quarterly Net Income (YoY)
23.34
Percentile Within Market, Percent Growth in Annual Net Income
0.26
Percentiles Within Market of Fundamental Ratios and Percentages
Percentile Within Market, PE Ratio (Current Year Earnings Estimate)
Percentile Within Market, PE Ratio (Trailing 12 Months)
Percentile Within Market, PEG Ratio (Long Term Growth Estimate)
Percentile Within Market, Price to Sales Ratio (Trailing 12 Months)
99.67
Percentile Within Market, Price to Book Ratio (Most Recent Quarterly Book Value per Share)
62.12
Percentile Within Market, Price to Cash Ratio (Most Recent Annual Cash Flow per Share)
Percentile Within Market, Pre-Tax Margin (Trailing 12 Months)
1.56
Percentile Within Market, Net Margin (Trailing 12 Months)
0.51
Percentile Within Market, Return on Equity (Trailing 12 Months)
21.86
Percentile Within Market, Return on Assets (Trailing 12 Months)
18.75
Percentile Within Market, Current Ratio (Most Recent Fiscal Quarter)
98.08
Percentile Within Market, Quick Ratio (Most Recent Fiscal Quarter)
98.15
Percentile Within Market, Debt to Common Equity (Most Recent Fiscal Quarter)
30.93
Percentile Within Market, Inventory Turnover (Trailing 12 Months)
Percentile Within Market, Dividend Yield (Based on Last Quarter)
61.82
Percentile Within Market, Percentage Held By Insiders (Latest Annual Proxy Report)
45.09
Percentile Within Market, Percentage Held By Institutions (Latest 13F Reports)