Spero Therapeutics, Inc. (SPRO)

Last Closing Price: 2.29 (2026-03-05)

Profile
Ticker
SPRO
Security Name
Spero Therapeutics, Inc.
Exchange
NASDAQ
Sector
Healthcare
Industry
Biotechnology
Free Float
53,240,000
Market Capitalization
129,020,000
Average Volume (Last 20 Days)
317,414
Beta (Past 60 Months)
1.45
Percentage Held By Insiders (Latest Annual Proxy Report)
5.50
Percentage Held By Institutions (Latest 13F Reports)
25.60
Recent Price/Volume
Closing Price
2.29
Opening Price
2.26
High Price
2.30
Low Price
2.22
Volume
178,000
Previous Closing Price
2.29
Previous Opening Price
2.21
Previous High Price
2.31
Previous Low Price
2.20
Previous Volume
315,000
High/Low Price
52-Week High Price
3.22
26-Week High Price
2.75
13-Week High Price
2.65
4-Week High Price
2.44
2-Week High Price
2.39
1-Week High Price
2.31
52-Week Low Price
0.51
26-Week Low Price
1.84
13-Week Low Price
2.10
4-Week Low Price
2.11
2-Week Low Price
2.11
1-Week Low Price
2.11
High/Low Volume
52-Week High Volume
183,498,000
26-Week High Volume
12,750,000
13-Week High Volume
1,028,000
4-Week High Volume
1,028,000
2-Week High Volume
683,000
1-Week High Volume
315,000
52-Week Low Volume
17,820
26-Week Low Volume
90,000
13-Week Low Volume
90,000
4-Week Low Volume
104,000
2-Week Low Volume
159,000
1-Week Low Volume
178,000
Money Flow
Total Money Flow, Past 52 Weeks
823,543,874
Total Money Flow, Past 26 Weeks
134,555,939
Total Money Flow, Past 13 Weeks
40,731,122
Total Money Flow, Past 4 Weeks
13,250,912
Total Money Flow, Past 2 Weeks
6,964,133
Total Money Flow, Past Week
2,677,472
Total Money Flow, 1 Day
404,060
Total Volume
Total Volume, Past 52 Weeks
356,410,731
Total Volume, Past 26 Weeks
58,134,000
Total Volume, Past 13 Weeks
17,484,000
Total Volume, Past 4 Weeks
5,778,000
Total Volume, Past 2 Weeks
3,126,000
Total Volume, Past Week
1,208,000
Percent Change in Price
Percent Change in Price, Past 52 Weeks
190.61
Percent Change in Price, Past 26 Weeks
7.01
Percent Change in Price, Past 13 Weeks
0.44
Percent Change in Price, Past 4 Weeks
-0.43
Percent Change in Price, Past 2 Weeks
-4.58
Percent Change in Price, Past Week
3.62
Percent Change in Price, 1 Day
0.00
New High/Low in Price
Reached New 52-Week High Price
False
Reached New 26-Week High Price
False
Reached New 13-Week High Price
False
Reached New 4-Week High Price
False
Reached New 2-Week High Price
False
Reached New 1-Week High Price
False
Reached New 52-Week Low Price
False
Reached New 26-Week Low Price
False
Reached New 13-Week Low Price
False
Reached New 4-Week Low Price
False
Reached New 2-Week Low Price
False
Reached New 1-Week Low Price
False
Consecutive Days/Weeks of Increasing/Decreasing Price
Consecutive Days of Increasing Price
0
Consecutive Weeks of Increasing Price
1
Consecutive Days of Decreasing Price
0
Consecutive Weeks of Decreasing Price
0
Consecutive Days/Weeks of Increasing/Decreasing Volume
Consecutive Days of Increasing Volume
0
Consecutive Weeks of Increasing Volume
0
Consecutive Days of Decreasing Volume
1
Consecutive Weeks of Decreasing Volume
1
New High/Low in Volume
Had New 52-Week High Volume
False
Had New 26-Week High Volume
False
Had New 13-Week High Volume
False
Had New 4-Week High Volume
False
Had New 2-Week High Volume
False
Had New 1-Week High Volume
False
Had New 52-Week Low Volume
False
Had New 26-Week Low Volume
False
Had New 13-Week Low Volume
False
Had New 4-Week Low Volume
False
Had New 2-Week Low Volume
False
Had New 1-Week Low Volume
True
Moving Averages
Simple Moving Average (5-Day)
2.23
Simple Moving Average (10-Day)
2.23
Simple Moving Average (20-Day)
2.30
Simple Moving Average (50-Day)
2.35
Simple Moving Average (100-Day)
2.35
Simple Moving Average (200-Day)
2.29
Previous Simple Moving Average (5-Day)
2.21
Previous Simple Moving Average (10-Day)
2.24
Previous Simple Moving Average (20-Day)
2.30
Previous Simple Moving Average (50-Day)
2.35
Previous Simple Moving Average (100-Day)
2.35
Previous Simple Moving Average (200-Day)
2.28
Technical Indicators
MACD (12, 26, 9)
-0.03
MACD (12, 26, 9) Signal
-0.03
Previous MACD (12, 26, 9)
-0.04
Previous MACD (12, 26, 9) Signal
-0.03
RSI (14-Day)
49.87
Previous RSI (14-Day)
49.87
Stochastic (14, 3, 3) %K
44.85
Stochastic (14, 3, 3) %D
32.18
Previous Stochastic (14, 3, 3) %K
33.86
Previous Stochastic (14, 3, 3) %D
22.78
Upper Bollinger Band (20, 2)
2.45
Lower Bollinger Band (20, 2)
2.15
Previous Upper Bollinger Band (20, 2)
2.45
Previous Lower Bollinger Band (20, 2)
2.15
Income Statement Financials
Quarterly Revenue (MRQ)
5,442,000
Quarterly Net Income (MRQ)
-7,382,000
Previous Quarterly Revenue (QoQ)
14,189,000
Previous Quarterly Revenue (YoY)
13,469,000
Previous Quarterly Net Income (QoQ)
-1,700,000
Previous Quarterly Net Income (YoY)
-17,147,000
Revenue (MRY)
47,977,000
Net Income (MRY)
-68,566,000
Previous Annual Revenue
103,781,000
Previous Net Income
22,806,000
Cost of Goods Sold (MRY)
Gross Profit (MRY)
47,977,000
Operating Expenses (MRY)
121,338,000
Operating Income (MRY)
-73,361,000
Non-Operating Income/Expense (MRY)
4,795,000
Pre-Tax Income (MRY)
-68,566,000
Normalized Pre-Tax Income (MRY)
-68,566,000
Income after Taxes (MRY)
-68,566,000
Income from Continuous Operations (MRY)
-68,566,000
Consolidated Net Income/Loss (MRY)
-68,566,000
Normalized Income after Taxes (MRY)
-68,566,000
EBIT (MRY)
-73,361,000
EBITDA (MRY)
-73,359,000
Balance Sheet Financials
Current Assets (MRQ)
52,323,000
Property, Plant, and Equipment (MRQ)
Long-Term Assets (MRQ)
1,847,000
Total Assets (MRQ)
54,170,000
Current Liabilities (MRQ)
13,649,000
Long-Term Debt (MRQ)
Long-Term Liabilities (MRQ)
14,027,000
Total Liabilities (MRQ)
27,676,000
Common Equity (MRQ)
26,494,000
Tangible Shareholders Equity (MRQ)
26,494,000
Shareholders Equity (MRQ)
26,494,000
Common Shares Outstanding (MRQ)
56,312,000
Cash Flow Statement Financials
Cash Flow from Operating Activities (MRY)
-23,444,000
Cash Flow from Investing Activities (MRY)
Cash Flow from Financial Activities (MRY)
Beginning Cash (MRY)
76,333,000
End Cash (MRY)
52,889,000
Increase/Decrease in Cash (MRY)
-23,444,000
Fundamental Ratios
PE Ratio (Current Year Earnings Estimate)
PE Ratio (Trailing 12 Months)
PEG Ratio (Long Term Growth Estimate)
Price to Sales Ratio (Trailing 12 Months)
3.18
Price to Book Ratio (Most Recent Quarterly Book Value per Share)
4.86
Price to Cash Ratio (Most Recent Annual Cash Flow per Share)
Pre-Tax Margin (Trailing 12 Months)
-107.39
Net Margin (Trailing 12 Months)
-108.11
Return on Equity (Trailing 12 Months)
-125.91
Return on Assets (Trailing 12 Months)
-57.58
Current Ratio (Most Recent Fiscal Quarter)
3.83
Quick Ratio (Most Recent Fiscal Quarter)
3.83
Debt to Common Equity (Most Recent Fiscal Quarter)
0.00
Inventory Turnover (Trailing 12 Months)
Book Value per Share (Most Recent Fiscal Quarter)
0.85
Earnings
Fiscal Period End, Next Quarterly Earnings Report
2025-12-31
Quarterly Earnings per Share Estimate
Next Expected Quarterly Earnings Report Date
2026-03-26
Days Until Next Expected Quarterly Earnings Report
20
Fiscal Period End, Last Quarterly Earnings Report
2025-09-30
Last Quarterly Earnings per Share Estimate
-0.25
Last Quarterly Earnings per Share
-0.13
Last Quarterly Earnings Report Date
2025-11-13
Days Since Last Quarterly Earnings Report
113
Earnings per Share (Most Recent Fiscal Year)
-1.27
Diluted Earnings per Share (Trailing 12 Months)
-0.79
Dividends
Last Dividend Date
Last Dividend Amount
Days Since Last Dividend
Annual Dividend (Based on Last Quarter)
0.00
Dividend Yield (Based on Last Quarter)
0.00
Percent Growth in Revenue/Net Income
Percent Growth in Quarterly Revenue (QoQ)
-61.65
Percent Growth in Quarterly Revenue (YoY)
-59.60
Percent Growth in Annual Revenue
-53.77
Percent Growth in Quarterly Net Income (QoQ)
-334.24
Percent Growth in Quarterly Net Income (YoY)
56.95
Percent Growth in Annual Net Income
-400.65
New High/Low in Revenue/Net Income
New 5-Year High Annual Revenue
False
New 5-Year Low Annual Revenue
False
New 5-Year High Quarterly Revenue (QoQ)
False
New 5-Year Low Quarterly Revenue (QoQ)
False
New 5-Year High Quarterly Revenue (YoY)
False
New 5-Year Low Quarterly Revenue (YoY)
False
New 5-Year High Annual Net Income
False
New 5-Year Low Annual Net Income
False
New 5-Year High Quarterly Net Income (QoQ)
False
New 5-Year Low Quarterly Net Income (QoQ)
False
New 5-Year High Quarterly Net Income (YoY)
False
New 5-Year Low Quarterly Net Income (YoY)
False
Consecutive Quarters/Years of Increasing/Decreasing Revenue/Net Income
Consecutive Quarters of Increasing Revenue (QoQ)
0
Consecutive Quarters of Decreasing Revenue (QoQ)
1
Consecutive Quarters of Increasing Revenue (YoY)
0
Consecutive Quarters of Decreasing Revenue (YoY)
1
Consecutive Years of Increasing Revenue
0
Consecutive Years of Decreasing Revenue
1
Consecutive Quarters of Increasing Net Income (QoQ)
0
Consecutive Quarters of Decreasing Net Income (QoQ)
1
Consecutive Quarters of Increasing Net Income (YoY)
2
Consecutive Quarters of Decreasing Net Income (YoY)
0
Consecutive Years of Increasing Net Income
0
Consecutive Years of Decreasing Net Income
1
Splits
Last Split Date (if within past year)
Last Split Ratio (if within past year)
Days Since Last Split (if within past year)
Volatility Metrics
Historical Volatility (Close-to-Close) (10-Day)
0.2946
Historical Volatility (Close-to-Close) (20-Day)
0.3572
Historical Volatility (Close-to-Close) (30-Day)
0.4181
Historical Volatility (Close-to-Close) (60-Day)
0.4325
Historical Volatility (Close-to-Close) (90-Day)
0.3804
Historical Volatility (Close-to-Close) (120-Day)
0.4260
Historical Volatility (Close-to-Close) (150-Day)
0.4659
Historical Volatility (Close-to-Close) (180-Day)
0.4589
Historical Volatility (Parkinson) (10-Day)
0.4109
Historical Volatility (Parkinson) (20-Day)
0.4188
Historical Volatility (Parkinson) (30-Day)
0.4621
Historical Volatility (Parkinson) (60-Day)
0.4480
Historical Volatility (Parkinson) (90-Day)
0.4135
Historical Volatility (Parkinson) (120-Day)
0.4422
Historical Volatility (Parkinson) (150-Day)
0.4676
Historical Volatility (Parkinson) (180-Day)
0.4747
Implied Volatility (Calls) (10-Day)
Implied Volatility (Calls) (20-Day)
0.6712
Implied Volatility (Calls) (30-Day)
0.6712
Implied Volatility (Calls) (60-Day)
0.6712
Implied Volatility (Calls) (90-Day)
0.6713
Implied Volatility (Calls) (120-Day)
0.6714
Implied Volatility (Calls) (150-Day)
Implied Volatility (Calls) (180-Day)
Implied Volatility (Puts) (10-Day)
Implied Volatility (Puts) (20-Day)
1.0141
Implied Volatility (Puts) (30-Day)
1.0141
Implied Volatility (Puts) (60-Day)
1.0141
Implied Volatility (Puts) (90-Day)
1.0140
Implied Volatility (Puts) (120-Day)
1.0139
Implied Volatility (Puts) (150-Day)
Implied Volatility (Puts) (180-Day)
Implied Volatility (Mean) (10-Day)
Implied Volatility (Mean) (20-Day)
0.8426
Implied Volatility (Mean) (30-Day)
0.8426
Implied Volatility (Mean) (60-Day)
0.8426
Implied Volatility (Mean) (90-Day)
0.8426
Implied Volatility (Mean) (120-Day)
0.8426
Implied Volatility (Mean) (150-Day)
Implied Volatility (Mean) (180-Day)
Put-Call Implied Volatility Ratio (10-Day)
Put-Call Implied Volatility Ratio (20-Day)
1.5108
Put-Call Implied Volatility Ratio (30-Day)
1.5108
Put-Call Implied Volatility Ratio (60-Day)
1.5108
Put-Call Implied Volatility Ratio (90-Day)
1.5106
Put-Call Implied Volatility Ratio (120-Day)
1.5101
Put-Call Implied Volatility Ratio (150-Day)
Put-Call Implied Volatility Ratio (180-Day)
Implied Volatility Skew (10-Day)
Implied Volatility Skew (20-Day)
Implied Volatility Skew (30-Day)
Implied Volatility Skew (60-Day)
0.0069
Implied Volatility Skew (90-Day)
0.0194
Implied Volatility Skew (120-Day)
0.0320
Implied Volatility Skew (150-Day)
Implied Volatility Skew (180-Day)
Option Statistics
Put-Call Ratio (Volume) (10-Day)
Put-Call Ratio (Volume) (20-Day)
0.0000
Put-Call Ratio (Volume) (30-Day)
0.0000
Put-Call Ratio (Volume) (60-Day)
0.0000
Put-Call Ratio (Volume) (90-Day)
0.0000
Put-Call Ratio (Volume) (120-Day)
0.0000
Put-Call Ratio (Volume) (150-Day)
Put-Call Ratio (Volume) (180-Day)
Put-Call Ratio (Open Interest) (10-Day)
0.2016
Put-Call Ratio (Open Interest) (20-Day)
0.2514
Put-Call Ratio (Open Interest) (30-Day)
0.3510
Put-Call Ratio (Open Interest) (60-Day)
0.3936
Put-Call Ratio (Open Interest) (90-Day)
0.2402
Put-Call Ratio (Open Interest) (120-Day)
0.0867
Put-Call Ratio (Open Interest) (150-Day)
0.0124
Put-Call Ratio (Open Interest) (180-Day)
0.0075
Percentiles Within Industry of Price Performance
Percentile Within Industry, Percent Change in Price, Past 52 Weeks
90.40
Percentile Within Industry, Percent Change in Price, Past 26 Weeks
56.29
Percentile Within Industry, Percent Change in Price, Past 13 Weeks
64.24
Percentile Within Industry, Percent Change in Price, Past 4 Weeks
40.07
Percentile Within Industry, Percent Change in Price, Past 2 Weeks
38.91
Percentile Within Industry, Percent Change in Price, Past Week
82.12
Percentile Within Industry, Percent Change in Price, 1 Day
77.48
Percentiles Within Industry of Revenue/Net Income Growth
Percentile Within Industry, Percent Growth in Quarterly Revenue (QoQ)
10.16
Percentile Within Industry, Percent Growth in Quarterly Revenue (YoY)
19.42
Percentile Within Industry, Percent Growth in Annual Revenue
15.28
Percentile Within Industry, Percent Growth in Quarterly Net Income (QoQ)
4.30
Percentile Within Industry, Percent Growth in Quarterly Net Income (YoY)
84.42
Percentile Within Industry, Percent Growth in Annual Net Income
3.37
Percentiles Within Industry of Fundamental Ratios and Percentages
Percentile Within Industry, PE Ratio (Current Year Earnings Estimate)
Percentile Within Industry, PE Ratio (Trailing 12 Months)
Percentile Within Industry, PEG Ratio (Long Term Growth Estimate)
Percentile Within Industry, Price to Sales Ratio (Trailing 12 Months)
21.40
Percentile Within Industry, Price to Book Ratio (Most Recent Quarterly Book Value per Share)
69.77
Percentile Within Industry, Price to Cash Ratio (Most Recent Annual Cash Flow per Share)
Percentile Within Industry, Pre-Tax Margin (Trailing 12 Months)
65.43
Percentile Within Industry, Net Margin (Trailing 12 Months)
56.43
Percentile Within Industry, Return on Equity (Trailing 12 Months)
31.57
Percentile Within Industry, Return on Assets (Trailing 12 Months)
43.45
Percentile Within Industry, Current Ratio (Most Recent Fiscal Quarter)
41.83
Percentile Within Industry, Quick Ratio (Most Recent Fiscal Quarter)
42.24
Percentile Within Industry, Debt to Common Equity (Most Recent Fiscal Quarter)
70.40
Percentile Within Industry, Inventory Turnover (Trailing 12 Months)
Percentile Within Industry, Dividend Yield (Based on Last Quarter)
99.17
Percentile Within Industry, Percentage Held By Insiders (Latest Annual Proxy Report)
35.17
Percentile Within Industry, Percentage Held By Institutions (Latest 13F Reports)
36.88
Percentiles Within Sector of Price Performance
Percentile Within Sector, Percent Change in Price, Past 52 Weeks
93.70
Percentile Within Sector, Percent Change in Price, Past 26 Weeks
61.43
Percentile Within Sector, Percent Change in Price, Past 13 Weeks
64.82
Percentile Within Sector, Percent Change in Price, Past 4 Weeks
45.91
Percentile Within Sector, Percent Change in Price, Past 2 Weeks
40.17
Percentile Within Sector, Percent Change in Price, Past Week
82.41
Percentile Within Sector, Percent Change in Price, 1 Day
77.42
Percentiles Within Sector of Revenue/Net Income Growth
Percentile Within Sector, Percent Growth in Quarterly Revenue (QoQ)
5.25
Percentile Within Sector, Percent Growth in Quarterly Revenue (YoY)
8.27
Percentile Within Sector, Percent Growth in Annual Revenue
7.24
Percentile Within Sector, Percent Growth in Quarterly Net Income (QoQ)
6.05
Percentile Within Sector, Percent Growth in Quarterly Net Income (YoY)
81.69
Percentile Within Sector, Percent Growth in Annual Net Income
4.62
Percentiles Within Sector of Fundamental Ratios and Percentages
Percentile Within Sector, PE Ratio (Current Year Earnings Estimate)
Percentile Within Sector, PE Ratio (Trailing 12 Months)
Percentile Within Sector, PEG Ratio (Long Term Growth Estimate)
Percentile Within Sector, Price to Sales Ratio (Trailing 12 Months)
47.97
Percentile Within Sector, Price to Book Ratio (Most Recent Quarterly Book Value per Share)
72.25
Percentile Within Sector, Price to Cash Ratio (Most Recent Annual Cash Flow per Share)
Percentile Within Sector, Pre-Tax Margin (Trailing 12 Months)
38.79
Percentile Within Sector, Net Margin (Trailing 12 Months)
30.19
Percentile Within Sector, Return on Equity (Trailing 12 Months)
25.36
Percentile Within Sector, Return on Assets (Trailing 12 Months)
32.24
Percentile Within Sector, Current Ratio (Most Recent Fiscal Quarter)
55.66
Percentile Within Sector, Quick Ratio (Most Recent Fiscal Quarter)
58.34
Percentile Within Sector, Debt to Common Equity (Most Recent Fiscal Quarter)
55.45
Percentile Within Sector, Inventory Turnover (Trailing 12 Months)
Percentile Within Sector, Dividend Yield (Based on Last Quarter)
93.02
Percentile Within Sector, Percentage Held By Insiders (Latest Annual Proxy Report)
41.59
Percentile Within Sector, Percentage Held By Institutions (Latest 13F Reports)
34.93
Percentiles Within Market of Price Performance
Percentile Within Market, Percent Change in Price, Past 52 Weeks
97.70
Percentile Within Market, Percent Change in Price, Past 26 Weeks
64.83
Percentile Within Market, Percent Change in Price, Past 13 Weeks
45.68
Percentile Within Market, Percent Change in Price, Past 4 Weeks
38.55
Percentile Within Market, Percent Change in Price, Past 2 Weeks
24.38
Percentile Within Market, Percent Change in Price, Past Week
88.43
Percentile Within Market, Percent Change in Price, 1 Day
79.19
Percentiles Within Market of Revenue/Net Income Growth
Percentile Within Market, Percent Growth in Quarterly Revenue (QoQ)
2.19
Percentile Within Market, Percent Growth in Quarterly Revenue (YoY)
2.65
Percentile Within Market, Percent Growth in Annual Revenue
3.04
Percentile Within Market, Percent Growth in Quarterly Net Income (QoQ)
5.91
Percentile Within Market, Percent Growth in Quarterly Net Income (YoY)
73.96
Percentile Within Market, Percent Growth in Annual Net Income
5.85
Percentiles Within Market of Fundamental Ratios and Percentages
Percentile Within Market, PE Ratio (Current Year Earnings Estimate)
Percentile Within Market, PE Ratio (Trailing 12 Months)
Percentile Within Market, PEG Ratio (Long Term Growth Estimate)
Percentile Within Market, Price to Sales Ratio (Trailing 12 Months)
66.93
Percentile Within Market, Price to Book Ratio (Most Recent Quarterly Book Value per Share)
79.06
Percentile Within Market, Price to Cash Ratio (Most Recent Annual Cash Flow per Share)
Percentile Within Market, Pre-Tax Margin (Trailing 12 Months)
12.46
Percentile Within Market, Net Margin (Trailing 12 Months)
9.67
Percentile Within Market, Return on Equity (Trailing 12 Months)
8.89
Percentile Within Market, Return on Assets (Trailing 12 Months)
9.94
Percentile Within Market, Current Ratio (Most Recent Fiscal Quarter)
78.96
Percentile Within Market, Quick Ratio (Most Recent Fiscal Quarter)
81.59
Percentile Within Market, Debt to Common Equity (Most Recent Fiscal Quarter)
31.32
Percentile Within Market, Inventory Turnover (Trailing 12 Months)
Percentile Within Market, Dividend Yield (Based on Last Quarter)
61.93
Percentile Within Market, Percentage Held By Insiders (Latest Annual Proxy Report)
50.70
Percentile Within Market, Percentage Held By Institutions (Latest 13F Reports)
29.43