Spyre Therapeutics, Inc. (SYRE)

Last Closing Price: 15.28 (2025-05-30)

Profile
Ticker
SYRE
Security Name
Spyre Therapeutics, Inc.
Exchange
NASDAQ
Sector
Healthcare
Industry
Biotechnology
Free Float
50,975,000
Market Capitalization
937,280,000
Average Volume (Last 20 Days)
470,958
Beta (Past 60 Months)
2.78
Percentage Held By Insiders (Latest Annual Proxy Report)
15.43
Percentage Held By Institutions (Latest 13F Reports)
80.39
Recent Price/Volume
Closing Price
15.28
Opening Price
15.34
High Price
15.43
Low Price
14.75
Volume
381,000
Previous Closing Price
15.55
Previous Opening Price
15.30
Previous High Price
15.71
Previous Low Price
15.05
Previous Volume
299,000
High/Low Price
52-Week High Price
40.26
26-Week High Price
29.06
13-Week High Price
21.03
4-Week High Price
15.71
2-Week High Price
15.71
1-Week High Price
15.71
52-Week Low Price
10.91
26-Week Low Price
10.91
13-Week Low Price
10.91
4-Week Low Price
12.29
2-Week Low Price
14.59
1-Week Low Price
14.75
High/Low Volume
52-Week High Volume
6,107,419
26-Week High Volume
1,641,775
13-Week High Volume
1,641,775
4-Week High Volume
1,034,547
2-Week High Volume
704,000
1-Week High Volume
704,000
52-Week Low Volume
184,120
26-Week Low Volume
210,226
13-Week Low Volume
210,226
4-Week Low Volume
210,226
2-Week Low Volume
210,226
1-Week Low Volume
299,000
Money Flow
Total Money Flow, Past 52 Weeks
3,623,999,880
Total Money Flow, Past 26 Weeks
1,420,816,550
Total Money Flow, Past 13 Weeks
640,334,700
Total Money Flow, Past 4 Weeks
135,148,932
Total Money Flow, Past 2 Weeks
50,371,906
Total Money Flow, Past Week
27,640,436
Total Money Flow, 1 Day
5,773,674
Total Volume
Total Volume, Past 52 Weeks
152,598,505
Total Volume, Past 26 Weeks
75,498,958
Total Volume, Past 13 Weeks
41,568,051
Total Volume, Past 4 Weeks
9,299,490
Total Volume, Past 2 Weeks
3,333,789
Total Volume, Past Week
1,819,228
Percent Change in Price
Percent Change in Price, Past 52 Weeks
-56.28
Percent Change in Price, Past 26 Weeks
-46.25
Percent Change in Price, Past 13 Weeks
-22.44
Percent Change in Price, Past 4 Weeks
1.13
Percent Change in Price, Past 2 Weeks
0.66
Percent Change in Price, Past Week
1.80
Percent Change in Price, 1 Day
-1.74
New High/Low in Price
Reached New 52-Week High Price
False
Reached New 26-Week High Price
False
Reached New 13-Week High Price
False
Reached New 4-Week High Price
False
Reached New 2-Week High Price
False
Reached New 1-Week High Price
False
Reached New 52-Week Low Price
False
Reached New 26-Week Low Price
False
Reached New 13-Week Low Price
False
Reached New 4-Week Low Price
False
Reached New 2-Week Low Price
False
Reached New 1-Week Low Price
True
Consecutive Days/Weeks of Increasing/Decreasing Price
Consecutive Days of Increasing Price
0
Consecutive Weeks of Increasing Price
1
Consecutive Days of Decreasing Price
1
Consecutive Weeks of Decreasing Price
0
Consecutive Days/Weeks of Increasing/Decreasing Volume
Consecutive Days of Increasing Volume
1
Consecutive Weeks of Increasing Volume
1
Consecutive Days of Decreasing Volume
0
Consecutive Weeks of Decreasing Volume
0
New High/Low in Volume
Had New 52-Week High Volume
False
Had New 26-Week High Volume
False
Had New 13-Week High Volume
False
Had New 4-Week High Volume
False
Had New 2-Week High Volume
False
Had New 1-Week High Volume
False
Had New 52-Week Low Volume
False
Had New 26-Week Low Volume
False
Had New 13-Week Low Volume
False
Had New 4-Week Low Volume
False
Had New 2-Week Low Volume
False
Had New 1-Week Low Volume
False
Moving Averages
Simple Moving Average (5-Day)
15.18
Simple Moving Average (10-Day)
15.12
Simple Moving Average (20-Day)
14.58
Simple Moving Average (50-Day)
14.69
Simple Moving Average (100-Day)
17.92
Simple Moving Average (200-Day)
23.33
Previous Simple Moving Average (5-Day)
15.14
Previous Simple Moving Average (10-Day)
15.05
Previous Simple Moving Average (20-Day)
14.55
Previous Simple Moving Average (50-Day)
14.75
Previous Simple Moving Average (100-Day)
18.01
Previous Simple Moving Average (200-Day)
23.37
Technical Indicators
MACD (12, 26, 9)
0.18
MACD (12, 26, 9) Signal
0.05
Previous MACD (12, 26, 9)
0.16
Previous MACD (12, 26, 9) Signal
0.02
RSI (14-Day)
54.02
Previous RSI (14-Day)
56.52
Stochastic (14, 3, 3) %K
83.21
Stochastic (14, 3, 3) %D
83.47
Previous Stochastic (14, 3, 3) %K
85.49
Previous Stochastic (14, 3, 3) %D
83.24
Upper Bollinger Band (20, 2)
16.32
Lower Bollinger Band (20, 2)
12.84
Previous Upper Bollinger Band (20, 2)
16.26
Previous Lower Bollinger Band (20, 2)
12.84
Income Statement Financials
Quarterly Revenue (MRQ)
Quarterly Net Income (MRQ)
-44,773,000
Previous Quarterly Revenue (QoQ)
Previous Quarterly Revenue (YoY)
Previous Quarterly Net Income (QoQ)
-56,296,000
Previous Quarterly Net Income (YoY)
-43,857,000
Revenue (MRY)
Net Income (MRY)
-208,018,000
Previous Annual Revenue
886,000
Previous Net Income
-338,790,000
Cost of Goods Sold (MRY)
Gross Profit (MRY)
Operating Expenses (MRY)
208,566,000
Operating Income (MRY)
-208,566,000
Non-Operating Income/Expense (MRY)
599,000
Pre-Tax Income (MRY)
-207,967,000
Normalized Pre-Tax Income (MRY)
-207,967,000
Income after Taxes (MRY)
-208,018,000
Income from Continuous Operations (MRY)
-208,018,000
Consolidated Net Income/Loss (MRY)
-208,018,000
Normalized Income after Taxes (MRY)
-208,018,000
EBIT (MRY)
-208,566,000
EBITDA (MRY)
-219,970,000
Balance Sheet Financials
Current Assets (MRQ)
569,768,000
Property, Plant, and Equipment (MRQ)
Long-Term Assets (MRQ)
10,000
Total Assets (MRQ)
569,778,000
Current Liabilities (MRQ)
70,678,000
Long-Term Debt (MRQ)
Long-Term Liabilities (MRQ)
16,490,000
Total Liabilities (MRQ)
87,168,000
Common Equity (MRQ)
326,790,000
Tangible Shareholders Equity (MRQ)
482,610,000
Shareholders Equity (MRQ)
482,610,000
Common Shares Outstanding (MRQ)
60,276,000
Cash Flow Statement Financials
Cash Flow from Operating Activities (MRY)
-157,410,000
Cash Flow from Investing Activities (MRY)
-353,285,000
Cash Flow from Financial Activities (MRY)
410,906,000
Beginning Cash (MRY)
189,215,000
End Cash (MRY)
89,423,000
Increase/Decrease in Cash (MRY)
-99,792,000
Fundamental Ratios
PE Ratio (Current Year Earnings Estimate)
PE Ratio (Trailing 12 Months)
PEG Ratio (Long Term Growth Estimate)
Price to Sales Ratio (Trailing 12 Months)
Price to Book Ratio (Most Recent Quarterly Book Value per Share)
2.87
Price to Cash Ratio (Most Recent Annual Cash Flow per Share)
Pre-Tax Margin (Trailing 12 Months)
Net Margin (Trailing 12 Months)
Return on Equity (Trailing 12 Months)
-77.46
Return on Assets (Trailing 12 Months)
-41.06
Current Ratio (Most Recent Fiscal Quarter)
8.06
Quick Ratio (Most Recent Fiscal Quarter)
8.06
Debt to Common Equity (Most Recent Fiscal Quarter)
0.00
Inventory Turnover (Trailing 12 Months)
Book Value per Share (Most Recent Fiscal Quarter)
5.42
Earnings
Fiscal Period End, Next Quarterly Earnings Report
2025-06-30
Quarterly Earnings per Share Estimate
-0.64
Next Expected Quarterly Earnings Report Date
2025-08-06
Days Until Next Expected Quarterly Earnings Report
67
Fiscal Period End, Last Quarterly Earnings Report
2025-03-31
Last Quarterly Earnings per Share Estimate
-0.76
Last Quarterly Earnings per Share
-0.74
Last Quarterly Earnings Report Date
2025-05-08
Days Since Last Quarterly Earnings Report
23
Earnings per Share (Most Recent Fiscal Year)
-3.18
Diluted Earnings per Share (Trailing 12 Months)
-3.77
Dividends
Last Dividend Date
Last Dividend Amount
Days Since Last Dividend
Annual Dividend (Based on Last Quarter)
0.00
Dividend Yield (Based on Last Quarter)
0.00
Percent Growth in Revenue/Net Income
Percent Growth in Quarterly Revenue (QoQ)
Percent Growth in Quarterly Revenue (YoY)
Percent Growth in Annual Revenue
Percent Growth in Quarterly Net Income (QoQ)
20.47
Percent Growth in Quarterly Net Income (YoY)
-2.09
Percent Growth in Annual Net Income
38.60
New High/Low in Revenue/Net Income
New 5-Year High Annual Revenue
False
New 5-Year Low Annual Revenue
False
New 5-Year High Quarterly Revenue (QoQ)
False
New 5-Year Low Quarterly Revenue (QoQ)
False
New 5-Year High Quarterly Revenue (YoY)
False
New 5-Year Low Quarterly Revenue (YoY)
False
New 5-Year High Annual Net Income
False
New 5-Year Low Annual Net Income
False
New 5-Year High Quarterly Net Income (QoQ)
False
New 5-Year Low Quarterly Net Income (QoQ)
False
New 5-Year High Quarterly Net Income (YoY)
False
New 5-Year Low Quarterly Net Income (YoY)
True
Consecutive Quarters/Years of Increasing/Decreasing Revenue/Net Income
Consecutive Quarters of Increasing Revenue (QoQ)
2
Consecutive Quarters of Decreasing Revenue (QoQ)
0
Consecutive Quarters of Increasing Revenue (YoY)
0
Consecutive Quarters of Decreasing Revenue (YoY)
1
Consecutive Years of Increasing Revenue
0
Consecutive Years of Decreasing Revenue
3
Consecutive Quarters of Increasing Net Income (QoQ)
2
Consecutive Quarters of Decreasing Net Income (QoQ)
0
Consecutive Quarters of Increasing Net Income (YoY)
0
Consecutive Quarters of Decreasing Net Income (YoY)
1
Consecutive Years of Increasing Net Income
1
Consecutive Years of Decreasing Net Income
0
Splits
Last Split Date (if within past year)
Last Split Ratio (if within past year)
Days Since Last Split (if within past year)
Volatility Metrics
Historical Volatility (Close-to-Close) (10-Day)
0.3756
Historical Volatility (Close-to-Close) (20-Day)
0.4422
Historical Volatility (Close-to-Close) (30-Day)
0.7171
Historical Volatility (Close-to-Close) (60-Day)
0.8359
Historical Volatility (Close-to-Close) (90-Day)
0.8063
Historical Volatility (Close-to-Close) (120-Day)
0.7568
Historical Volatility (Close-to-Close) (150-Day)
0.7233
Historical Volatility (Close-to-Close) (180-Day)
0.7138
Historical Volatility (Parkinson) (10-Day)
0.4094
Historical Volatility (Parkinson) (20-Day)
0.4746
Historical Volatility (Parkinson) (30-Day)
0.6525
Historical Volatility (Parkinson) (60-Day)
0.7884
Historical Volatility (Parkinson) (90-Day)
0.7833
Historical Volatility (Parkinson) (120-Day)
0.7670
Historical Volatility (Parkinson) (150-Day)
0.7483
Historical Volatility (Parkinson) (180-Day)
0.7332
Implied Volatility (Calls) (10-Day)
0.9728
Implied Volatility (Calls) (20-Day)
0.9728
Implied Volatility (Calls) (30-Day)
1.0197
Implied Volatility (Calls) (60-Day)
1.0573
Implied Volatility (Calls) (90-Day)
0.8901
Implied Volatility (Calls) (120-Day)
0.7589
Implied Volatility (Calls) (150-Day)
0.7269
Implied Volatility (Calls) (180-Day)
0.6950
Implied Volatility (Puts) (10-Day)
0.7491
Implied Volatility (Puts) (20-Day)
0.7491
Implied Volatility (Puts) (30-Day)
0.7130
Implied Volatility (Puts) (60-Day)
0.6678
Implied Volatility (Puts) (90-Day)
0.7527
Implied Volatility (Puts) (120-Day)
0.8017
Implied Volatility (Puts) (150-Day)
0.7509
Implied Volatility (Puts) (180-Day)
0.7002
Implied Volatility (Mean) (10-Day)
0.8610
Implied Volatility (Mean) (20-Day)
0.8610
Implied Volatility (Mean) (30-Day)
0.8663
Implied Volatility (Mean) (60-Day)
0.8625
Implied Volatility (Mean) (90-Day)
0.8214
Implied Volatility (Mean) (120-Day)
0.7803
Implied Volatility (Mean) (150-Day)
0.7389
Implied Volatility (Mean) (180-Day)
0.6976
Put-Call Implied Volatility Ratio (10-Day)
0.7701
Put-Call Implied Volatility Ratio (20-Day)
0.7701
Put-Call Implied Volatility Ratio (30-Day)
0.6992
Put-Call Implied Volatility Ratio (60-Day)
0.6316
Put-Call Implied Volatility Ratio (90-Day)
0.8456
Put-Call Implied Volatility Ratio (120-Day)
1.0564
Put-Call Implied Volatility Ratio (150-Day)
1.0331
Put-Call Implied Volatility Ratio (180-Day)
1.0075
Implied Volatility Skew (10-Day)
Implied Volatility Skew (20-Day)
Implied Volatility Skew (30-Day)
Implied Volatility Skew (60-Day)
0.0746
Implied Volatility Skew (90-Day)
0.0652
Implied Volatility Skew (120-Day)
0.0590
Implied Volatility Skew (150-Day)
0.0620
Implied Volatility Skew (180-Day)
0.0649
Option Statistics
Put-Call Ratio (Volume) (10-Day)
0.0000
Put-Call Ratio (Volume) (20-Day)
0.0000
Put-Call Ratio (Volume) (30-Day)
0.0000
Put-Call Ratio (Volume) (60-Day)
Put-Call Ratio (Volume) (90-Day)
Put-Call Ratio (Volume) (120-Day)
Put-Call Ratio (Volume) (150-Day)
Put-Call Ratio (Volume) (180-Day)
Put-Call Ratio (Open Interest) (10-Day)
0.5488
Put-Call Ratio (Open Interest) (20-Day)
0.5488
Put-Call Ratio (Open Interest) (30-Day)
2.6224
Put-Call Ratio (Open Interest) (60-Day)
6.3598
Put-Call Ratio (Open Interest) (90-Day)
4.6138
Put-Call Ratio (Open Interest) (120-Day)
3.1282
Put-Call Ratio (Open Interest) (150-Day)
2.3590
Put-Call Ratio (Open Interest) (180-Day)
1.5897
Percentiles Within Industry of Price Performance
Percentile Within Industry, Percent Change in Price, Past 52 Weeks
39.26
Percentile Within Industry, Percent Change in Price, Past 26 Weeks
36.19
Percentile Within Industry, Percent Change in Price, Past 13 Weeks
36.35
Percentile Within Industry, Percent Change in Price, Past 4 Weeks
65.43
Percentile Within Industry, Percent Change in Price, Past 2 Weeks
48.95
Percentile Within Industry, Percent Change in Price, Past Week
58.16
Percentile Within Industry, Percent Change in Price, 1 Day
45.07
Percentiles Within Industry of Revenue/Net Income Growth
Percentile Within Industry, Percent Growth in Quarterly Revenue (QoQ)
Percentile Within Industry, Percent Growth in Quarterly Revenue (YoY)
Percentile Within Industry, Percent Growth in Annual Revenue
Percentile Within Industry, Percent Growth in Quarterly Net Income (QoQ)
71.53
Percentile Within Industry, Percent Growth in Quarterly Net Income (YoY)
51.96
Percentile Within Industry, Percent Growth in Annual Net Income
79.35
Percentiles Within Industry of Fundamental Ratios and Percentages
Percentile Within Industry, PE Ratio (Current Year Earnings Estimate)
Percentile Within Industry, PE Ratio (Trailing 12 Months)
Percentile Within Industry, PEG Ratio (Long Term Growth Estimate)
Percentile Within Industry, Price to Sales Ratio (Trailing 12 Months)
Percentile Within Industry, Price to Book Ratio (Most Recent Quarterly Book Value per Share)
64.53
Percentile Within Industry, Price to Cash Ratio (Most Recent Annual Cash Flow per Share)
Percentile Within Industry, Pre-Tax Margin (Trailing 12 Months)
Percentile Within Industry, Net Margin (Trailing 12 Months)
Percentile Within Industry, Return on Equity (Trailing 12 Months)
45.40
Percentile Within Industry, Return on Assets (Trailing 12 Months)
55.69
Percentile Within Industry, Current Ratio (Most Recent Fiscal Quarter)
68.57
Percentile Within Industry, Quick Ratio (Most Recent Fiscal Quarter)
68.74
Percentile Within Industry, Debt to Common Equity (Most Recent Fiscal Quarter)
73.43
Percentile Within Industry, Inventory Turnover (Trailing 12 Months)
Percentile Within Industry, Dividend Yield (Based on Last Quarter)
99.35
Percentile Within Industry, Percentage Held By Insiders (Latest Annual Proxy Report)
68.24
Percentile Within Industry, Percentage Held By Institutions (Latest 13F Reports)
74.29
Percentiles Within Sector of Price Performance
Percentile Within Sector, Percent Change in Price, Past 52 Weeks
31.12
Percentile Within Sector, Percent Change in Price, Past 26 Weeks
28.41
Percentile Within Sector, Percent Change in Price, Past 13 Weeks
34.49
Percentile Within Sector, Percent Change in Price, Past 4 Weeks
61.78
Percentile Within Sector, Percent Change in Price, Past 2 Weeks
56.26
Percentile Within Sector, Percent Change in Price, Past Week
57.94
Percentile Within Sector, Percent Change in Price, 1 Day
38.04
Percentiles Within Sector of Revenue/Net Income Growth
Percentile Within Sector, Percent Growth in Quarterly Revenue (QoQ)
Percentile Within Sector, Percent Growth in Quarterly Revenue (YoY)
Percentile Within Sector, Percent Growth in Annual Revenue
Percentile Within Sector, Percent Growth in Quarterly Net Income (QoQ)
68.29
Percentile Within Sector, Percent Growth in Quarterly Net Income (YoY)
48.02
Percentile Within Sector, Percent Growth in Annual Net Income
76.32
Percentiles Within Sector of Fundamental Ratios and Percentages
Percentile Within Sector, PE Ratio (Current Year Earnings Estimate)
Percentile Within Sector, PE Ratio (Trailing 12 Months)
Percentile Within Sector, PEG Ratio (Long Term Growth Estimate)
Percentile Within Sector, Price to Sales Ratio (Trailing 12 Months)
Percentile Within Sector, Price to Book Ratio (Most Recent Quarterly Book Value per Share)
61.85
Percentile Within Sector, Price to Cash Ratio (Most Recent Annual Cash Flow per Share)
Percentile Within Sector, Pre-Tax Margin (Trailing 12 Months)
Percentile Within Sector, Net Margin (Trailing 12 Months)
Percentile Within Sector, Return on Equity (Trailing 12 Months)
35.64
Percentile Within Sector, Return on Assets (Trailing 12 Months)
40.52
Percentile Within Sector, Current Ratio (Most Recent Fiscal Quarter)
78.22
Percentile Within Sector, Quick Ratio (Most Recent Fiscal Quarter)
79.11
Percentile Within Sector, Debt to Common Equity (Most Recent Fiscal Quarter)
57.34
Percentile Within Sector, Inventory Turnover (Trailing 12 Months)
Percentile Within Sector, Dividend Yield (Based on Last Quarter)
93.08
Percentile Within Sector, Percentage Held By Insiders (Latest Annual Proxy Report)
70.47
Percentile Within Sector, Percentage Held By Institutions (Latest 13F Reports)
70.71
Percentiles Within Market of Price Performance
Percentile Within Market, Percent Change in Price, Past 52 Weeks
8.68
Percentile Within Market, Percent Change in Price, Past 26 Weeks
7.98
Percentile Within Market, Percent Change in Price, Past 13 Weeks
11.32
Percentile Within Market, Percent Change in Price, Past 4 Weeks
43.15
Percentile Within Market, Percent Change in Price, Past 2 Weeks
74.62
Percentile Within Market, Percent Change in Price, Past Week
72.11
Percentile Within Market, Percent Change in Price, 1 Day
16.73
Percentiles Within Market of Revenue/Net Income Growth
Percentile Within Market, Percent Growth in Quarterly Revenue (QoQ)
Percentile Within Market, Percent Growth in Quarterly Revenue (YoY)
Percentile Within Market, Percent Growth in Annual Revenue
Percentile Within Market, Percent Growth in Quarterly Net Income (QoQ)
65.52
Percentile Within Market, Percent Growth in Quarterly Net Income (YoY)
45.30
Percentile Within Market, Percent Growth in Annual Net Income
71.79
Percentiles Within Market of Fundamental Ratios and Percentages
Percentile Within Market, PE Ratio (Current Year Earnings Estimate)
Percentile Within Market, PE Ratio (Trailing 12 Months)
Percentile Within Market, PEG Ratio (Long Term Growth Estimate)
Percentile Within Market, Price to Sales Ratio (Trailing 12 Months)
Percentile Within Market, Price to Book Ratio (Most Recent Quarterly Book Value per Share)
67.50
Percentile Within Market, Price to Cash Ratio (Most Recent Annual Cash Flow per Share)
Percentile Within Market, Pre-Tax Margin (Trailing 12 Months)
Percentile Within Market, Net Margin (Trailing 12 Months)
Percentile Within Market, Return on Equity (Trailing 12 Months)
13.30
Percentile Within Market, Return on Assets (Trailing 12 Months)
12.87
Percentile Within Market, Current Ratio (Most Recent Fiscal Quarter)
90.80
Percentile Within Market, Quick Ratio (Most Recent Fiscal Quarter)
91.41
Percentile Within Market, Debt to Common Equity (Most Recent Fiscal Quarter)
32.03
Percentile Within Market, Inventory Turnover (Trailing 12 Months)
Percentile Within Market, Dividend Yield (Based on Last Quarter)
60.28
Percentile Within Market, Percentage Held By Insiders (Latest Annual Proxy Report)
72.10
Percentile Within Market, Percentage Held By Institutions (Latest 13F Reports)
68.84