Return on Equity: The amount of net income returned as a percentage of shareholders equity. Return on equity measures a corporation's profitability by revealing how much profit a company generates with the money shareholders have invested. Calculated as: Income from Continuing Operations / Total Common Equity

Vanda Pharmaceuticals Inc. (VNDA) had Return on Equity of -67.38% for the most recently reported fiscal year, ending 2025-12-31.